Generally, supplemental VEA is protected within the digestive

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The chemical structure of VEA is comprised of hydrophilic acetate group and a long lipophilic chain contributing a lipo-hydrophilic property. Generally, supplemental VEA is protected within the digestive tract via a two-step metabolic course of (Fig. 2). First, VEA is de-acetylated by an esterase enzymatic reaction to vitamin E.